![]() ![]() Some trials compare a new treatment with a placebo. And not because of general differences in the people taking part. Then the researchers know that if one group does better than the other, it’s because of the different treatment. This makes sure that the groups are as similar as possible. the size of your cancer and how far it has spread (stage).The research team put information about the people taking part into the computer program. The results would look as if the one treatment works better than the other, but really it doesn't. This is because they were more unwell to begin with. The people in this group then may not do as well as people in another group. But it is possible to be biased without realising it.įor example, doctors may avoid putting patients who are more unwell into a particular trial group without really meaning to. Of course, researchers are unlikely to be deliberately biased. And that there is no bias that could distort the results. Researchers run randomised trials because they need to be sure that the results are correct. In this situation, the people in the control group would have a dummy treatment. This could be because people have already had all the treatments currently available. Sometimes there is no standard treatment available for the control group. A randomised trial that has a control group is called a randomised controlled trial (RCT). People in the other group (or groups) have a new treatment or procedure that is being tested. Often there is one group who have the standard treatment they would have if they weren’t in the trial. Most phase 3 trials and some phase 2 trials are randomised. This process is called 'randomisation' and is usually done by a computer. The people taking part are put into one of the groups at random. Randomised trials have at least 2 different treatment groups. ![]()
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